Journal: Cell Reports Medicine
Article Title: A longitudinal, multi-omic atlas reveals the emergence of a spatially organized immunosuppressive ecosystem in resistant melanoma
doi: 10.1016/j.xcrm.2026.102716
Figure Lengend Snippet: Overview of longitudinal tumor biopsies and multi-platform analysis (A) Longitudinal tumor specimens ( n = 45) from 10 patients with metastatic melanoma. (B and C) Treatment timelines and clinical events for the MGH patient 35 (Pt35) (B) and the MGH patient 42 (Pt42) (C). Pt35 is an R, and Pt42 is an NR to anti-PD-1 therapy. (D) Bulk tumor profiling workflow incorporating WES, RNA-seq, NanoString Vantage 3D, and RPPA. (E) Spatial analysis utilizing NanoString DSP, CyCIF, mIHC, and Visium HD. See also and .
Article Snippet: Visium HD Spatial Gene Expression Reagent Kit , 10x Genomics , PN-1000675.
Techniques: RNA Sequencing